Enzyme Detergent Instrument Cleaner
The highly concentrated Surgical Instrument Cleaner with Conditioners™ for cleaning Surgical Instruments. ONE Surgical Instrument Cleaner product, ONE Surgical Instrument Cleaner application. Apply it ONCE. It's all you really need to remove stains and cleaning Surgical Instruments cleaner. The all-in-ONE™ 4 Enzyme Detergent Surgical Instrument Cleaner with Conditioners™is a unique formulation of multi-tiered high-level enzymes, detergents, and a surfactant chemical complex to: clean surgical instruments, prevent corrosion, remove stains from surgical instruments, protect the surface, and lubricate the moving parts of surgical instruments. recommended for Laboratory Glassware Washers   
The all-in-ONE™ Dilution rate is .25 to .5 ounces per gallon
depending on level of bioburden, encrustation and stains.
The Neutral pH all-in-ONE™ Enzymatic Enzyme Detergent surgical instrument Cleaner rapidly breaks down bio-burden, cleans and conditions the surface and then... rinse clean.
Surgical Instrument Decontamination
Surgical Instrument Cleaner  
Surgical Instrument Cleaners with Conditioners™ for
cleaning surgical instruments cleaner.
Contact us for product information and pricing that will lower your surgical instrument cleaning costs and deliver the surgical instrument care that you and your surgical instruments deserve.
The ergo-Logistics
4 Enzyme Detergent Surgical Instrument Cleaner
The ergo-Logistics
4 Enzyme Detergent Surgical Instrument Cleaner
delivers the most rapid surgical instrument cleaning and endoscope cleaning with cost effective results, and we guarantee it.
The easy FOAM-it 4 Enzyme Detergent lays down a thick blanket of 4 long lasting Enzyme Detergents for cleaning surgical instruments cleaner, cost effectively and fast. No other surgical instrument cleaner delivers the cleaning and conditioning you will see from the all-in-ONE™ 4 Enzyme surgical instrument cleaner Detergent.
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What are Enzyme Detergent Cleaners ?
Enzymatic enzyme detergent cleaning time.
Enzymatic enzyme detergent optimal cost.
Enzyme Detergents for cleaning Endoscopes
Enzyme Detergent cleaners
Enzymatic enzyme detergents for cleaning surgical instruments.
Enzyme Detergent Surgical Instrument Cleaner 

4 Enzymes are necessary for cleaning surgical instruments cleaner.
  • Lipase Enzymes,
  • Amylase Enzymes,
  • Carbohydrase Enzymes, and
  • Protease Enzymes.

Enzyme Detergent cleaners should be:
  • Neutral pH,
  • 100% Biodegradable,
  • non irritating,
  • non hazardous,and
  • phosphate free

Enzyme Detergents
Enzymatic Detergents
non hazardous enzyme detergent
Enzymatic enzyme detergents for cleaning surgical instruments.
Enzyme Detergents for cleaning Endoscopes
Enzyme Detergent cleaners
Enzymatic enzyme detergents for cleaning surgical instruments.

The use of enzymes of various compositions and concentrations, in detergents is becoming common. Over half of all detergents presently available contain some level of enzymes.  The enzymatic enzyme detergent industry is the largest single market for enzymes, at rate of 25 - 30% of total sales. Details of which enzymes are used within enzymatic enzyme  detergents and the ways in which they are best used, are rarely been published.  Enzymatic enzyme detergents should: remove proteinaceous bioburden, dissolve mineral  encrustation, remove stains, and enhance the “passive layer” of stainless steel. Enzymatic enzyme detergents should be “free rinsing” to render a residue free surface and should  be designed to condition the source water to counter the potential pitting and staining effects of hard water. The primary goal of cleaning is to remove soil (proteinaceous  bioburden) which includes proteins, starches and lipids.

The all-in-ONE Surgical Instrument Cleaner 4 delivers the 4 enzymes needed to breakdown and remove all forms of proteinaceous bioburden. Four enzyme Surgical Instrument Cleaners are necessary to break down all forms of bioburden. Surgical Instrument Cleaners that do not deliver Lipase Surgical Instrument Cleaner Enzymes, Amylase Surgical Instrument Cleaner Enzymes, Carbohydrase Surgical Instrument Cleaner Enzymes, and Protease Surgical Instrument Cleaner Enzymes cannot remove all forms of surgical instrument proteinaceous bioburden. The single or dual enzyme surgical instrument cleaners cannot remove all forms of surgical instrument proteinaceous bioburden and they do not deliver the detergent surfactant agents that are critical for cleaning the surface of surgical instruments. These products include the single or dual enzyme surgical instrument cleaners and such products as the: Zymex enzyme surgical instrument cleaner, Miltex enzyme surgical instrument cleaner, Enzy-Clean enzyme surgical instrument cleaner, Scope-ZYME enzyme surgical instrument cleaner, MetriZyme enzyme surgical instrument cleaner, and STERIS Prolystica enzyme surgical instrument cleaner. The single or dual enzyme surgical instrument cleaners do not deliver the 4 enzymes needed to breakdown and remove all forms of proteinaceous bioburden.

Enzymatic enzyme detergent product claims of "fast acting enzyme" and "strongest enzyme" are typically erroneous. Enzymes all act at the same speed and are of equal strength.  The application of the products and diluted concentrations determine the speed and the strength as it relates to cleaning outcomes.

Common misunderstandings exist pertaining to the application of enzymatic enzyme detergents including the times and temperatures for optimal cleaning outcomes. There are  parameters for the use of enzymatic enzyme detergents that can render a high probability of excellent cleaning outcomes.

The high cost of high quality enzymatic enzyme detergents surgical instrument cleaning and endoscope cleaning products is reconciled by their performance and your cost benefit analysis will be reconciled by the savings in the quantity of enzymatic enzyme detergents you use.
  • Lower Inventory costs
  • lower shipping costs
  • labor cost savings
  • space cost savings
  • inventory reduction for the number of different products replaced
The all-in-ONE Surgical Instrument Cleaner delivers the most rapid surgical instrument cleaning and endoscope cleaning with cost effective results, and we guarantee it.

It is commonly stated that enzymes “clean”. Enzymes alone do not “clean”. The primary function of enzymes is to break down soil, usually proteinaceous bioburden. For a cleaning  product to “clean” surfactants are necessary that will remove the soil from the surface. A combination of enzymes and detergents is necessary for “cleaning”. Enzymes and  detergent combination products are referred to as “enzymatic enzyme detergents” or "all-in-one enzymatic enzyme detergents" . 

The optimal temperature for maximum enzymatic enzyme detergent cleaning performance peaks at 137 degrees Fahrenheit (58.33 degree Celsius). The detergent components typically  peak performance at 185 degrees Fahrenheit (85 degree Celsius). The peak performance for the enzymes and the detergents represent the top of a bell curve with increasing and  decreasing enzymatic enzyme detergent performance to each side the peak.

Enzyme Detergents for cleaning Endoscopes
Enzyme Detergent cleaners
Enzymatic enzyme detergents for cleaning surgical instruments.
Dosage rate claims as to the cleaning results promised from very small dosage rates of enzymatic enzyme detergent can be misleading. Due to the wide variance of potential  applications, the only dosage rates that can be attributed to a level of enzymatic enzyme detergent cleaning performance are those dosage rates that have been observed within  your facility to render the cleaning outcomes required. The optimal enzymatic enzyme detergent dosage rate (amount diluted per quantity of carrier solution, usually ounces per  gallon of neutral pH water) is a function of the types of enzymes and the concentration level of enzymes within the enzymatic enzyme detergent product. Detergents can render  inferior performance with higher levels of concentration. Enzymes can render better performance at higher levels of concentration. To determine the optimal (lowest dosage with  highest cleaning result) amount of enzymatic enzyme detergent to use, begin with the dosage recommended by the manufacture and then triturate the dosage higher or lower based on  your cleaning outcomes. The cost of enzymatic enzyme detergents products is reconciled by their performance and your cost benefit analysis will be reconciled by the savings in  the quantity of enzymatic enzyme detergents used.

Enzyme Detergent 
enzyme detergents for cleaning surgical instruments.

The optimal application time for maximum enzymatic enzyme detergent cleaning performance depends of the level of soil hydration/encrustation, the amount of soil, and the mass of  items being cleaned. Claims as to enzymatic enzyme detergent products “cleaning within minutes” are fallacious without specifics as to the above parameters.

Types of enzymes potentially used within enzymatic enzyme detergents:
Lipase Enzymes: (to breakdown fat) to cleave fatty acid residue from the glycerol residue in a neutral fat or a phospholipid.
Amylase Enzymes: (to breakdown starch) to catalyze the hydrolysis of starch to sugar to produce carbohydrate derivatives.
Carbohydrase Enzymes: (to breakdown starch to a lower level) to catalyze the hydrolysis of higher carbohydrates to lower forms
Protease Enzymes: (breakdown blood) including the proteinases and peptidases, to catalyze the hydrolytic breakdown of proteins.

The use of enzymatic enzyme detergents allows lower temperatures and shorter periods of mechanical cleaning to be employed, often after a preliminary period of soaking. In  general, enzyme detergents remove protein from clothes soiled with blood, milk, sweat, grass, etc. far more effectively than non-enzyme detergents. At present only proteases and  amylases are commonly used. Although a wide range of lipases is known, it is only very recently that lipases suitable for use in detergent preparations have been deployed.

This Surgical Instrument Cleaner complies with Surgical Instrument and Surgical Instrument Washer specifications and is classified as a non hazardous enzyme detergent Surgical Instrument Cleaner. This lowers shipping costs significantly and offers a 'gree' cleaner product.

Enzyme Detergents for cleaning Endoscopes
Enzyme Detergent cleaners
Enzymatic enzyme detergents for cleaning surgical instruments.
Enzymatic enzyme detergents must be cost-effective and safe to use.
The all-in-ONE Surgical Instrument Cleaner delivers the most rapid surgical instrument cleaning and endoscope cleaning with cost effective results, and we guarantee it.

Early attempts to use proteases floundered because users developed hypersensitivity. This was combated by developing dust-free granulates (about 0.5 mm in diameter) in which the  enzyme is incorporated into an inner core, containing inorganic salts (e.g. NaCI) and sugars as preservative, bound with reinforcing, fibers of carboxymethyl cellulose or  similar protective colloid. This core is coated with inert waxy materials made from paraffin oil or polyethylene glycol plus various hydrophilic binders, which later disperse in  the wash. This combination of materials both prevents dust formation and protects the enzymes against damage by other detergent components during storage. It has been reported  that spraying enzymatic enzyme detergent cleaning products has resulted in respiratory irritations. It is suspected that this is due to the enzyme aerosols. Applying the  enzymatic enzyme detergent in a liquid of foam state should avoid this potential complication.  

The “average” compositions of an enzymatic enzyme detergent product:
Constituent Composition (%)
Sodium tripolyphosphate (water softener, loosens dirt) 38.0%
Sodium alkane sulphonate (surfactant) 25.0%
Sodium perborate tetrahydrate (oxidising agent) 25.0%
Soap (sodium alkane carboxylates) 3.0%
Sodium sulphate (filler, water softener) 2.5%
Sodium carboxymethyl cellulose (dirt-suspending agent) 1.6%
Sodium metasilicate (binder, loosens dirt) 1.0%
Bacillus protease (3% active) 0.8%
Fluorescent brighteners 0.3
Foam-controlling agents Trace
Perfume (optional) Trace to cover the otherwise potentially unacceptable aromas
Coloring (optional) Trace to provide visual evidence to the user that product is present
Water to 100%
Enzyme Detergents
Enzymatic Detergents
Enzymatic enzyme detergents for cleaning surgical instruments.

A recent trend is to reduce this phosphate content within enzymatic enzyme detergents for environmental reasons. It may be replaced by sodium carbonate plus extra protease.  There is no reason that correlates with product efficacy for an enzymatic enzyme detergent to be other than "green".

The all-in-ONE Surgical Instrument Cleaner with Conditioners™
product is used worldwide for cleaning surgical instruments cleaner.
This cleaner is 100% biodegradable and Neutral pH.
The all-in-ONE Surgical Instrument Cleaner complies with Surgical Instrument and Surgical Instrument Washer specifications and is classified as a non hazardous enzyme detergent.
The all-in-ONE Surgical Instrument Cleaner enzymes used for enzymatic enzyme detergents are produced using species of Bacillus, mainly by just two companies. Novo Industri A/S produce and supply three proteases,  Alcalase, from B. licheniformis, Esperase, from an alkalophilic strain of a B. licheniformis and Savinase, from an alkalophilic strain of B. amyloliquefaciens (often mistakenly  attributed to B. subtilis). GistBrocades produce and supply Maxatase, from B. licheniformis. Alcalase and Maxatase (both mainly subtilisin) are recommended for use at 10-65°C  and pH 7-10.5. Savinase and Esperase may be used at up to pH 11 and 12, respectively. The a-amylase supplied for detergent use is Termamyl, the enzyme from B. licheniformis  which is also used in the production of glucose syrups. a-Amylase is particularly useful in washing glassware and with de-starching detergents.

Enzyme Detergents
Enzymatic Detergents
Enzymatic enzyme detergents for cleaning surgical instruments.
The all-in-ONE Surgical Instrument Cleaner

Enzymatic enzyme detergent preparations in a non-ionic surfactant are available for formulating in liquid 'spotting' concentrates, and are typically used for removing stubborn  stains. Preparations containing both Termamyl and Alcalase are produced. Termamyl is sufficiently resistant to proteolysis to retain activity long enough to fulfill its  function.

It should be noted that all the enzymatic enzyme detergent proteolytic enzymes described are fairly non-specific serine endoproteases, giving preferred cleavage on the carboxyl  side of hydrophobic amino acid residues but capable of hydrolysing most peptide links. They convert their substrates into small, readily soluble fragments which can be removed  easily from fabrics. Only serine protease; may be used in enzymatic enzyme detergent formulations: thiol proteases (e.g. papain) would be oxidized by the bleaching agents, and  metalloproteases (e.g. thermolysin) would lose their metal cofactors due to the reaction with the water softening agents or hydroxyl ions.

There are opportunities to extend the use of enzymatic enzyme detergents. The recent availability of a suitable lipase may increase the quantities of enzymes employed. There  are, perhaps, opportunities for enzymes such as glucose oxidase, lipoxygenase and glycerol oxidase as means of generating hydrogen peroxide in situ. Added peroxidases may aid  the bleaching efficacy of this peroxide.

Enzyme Detergents for cleaning Endoscopes
Enzyme Detergent cleaners
Enzymatic enzyme detergents for cleaning surgical instruments.

The high cost of high quality enzymatic enzyme detergents surgical instrument cleaning and endoscope cleaning products is reconciled by their performance and your cost benefit analysis will be reconciled by the savings in the quantity of enzymatic enzyme detergents you use.
  • Lower Inventory costs
  • lower shipping costs
  • labor cost savings
  • space cost savings
  • inventory reduction for the number of different products replaced
The all-in-ONE Surgical Instrument Cleaner delivers the most rapid surgical instrument cleaning and endoscope cleaning with cost effective results, and we guarantee it.